Researchers have found an effective target in the brain for electrical stimulation to improve mood in people suffering from depression. Stimulation of a brain region called the lateral orbitofrontal cortex (OFC) reliably produced acute improvement in mood in patients who suffered from depression at the start of the study.
"Ultimately, it would be ideal if activity in mood-related brain circuits could be normalized indefinitely without patients needing to do anything," Rao says.
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